Chip28 protein

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August undefined, 2024

WebPreston GM, Carroll TP, Guggino WB, Agre P. “Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein.” Science. 1992 Apr 17;256(5055):385-7. Agre P, Casella JF, Zinkham WH, McMillan C, Bennett V. “Partial deficiency of erythrocyte spectrin in hereditary spherocytosis.” Nature. 1985 Mar 28-Apr 3;314(6009):380-3. WebAug 25, 1992 · Water rapidly crosses the plasma membranes of red blood cells (RBCs) and renal tubules through highly specialized channels. CHIP28 is an abundant integral membrane protein in RBCs and renal tubules, and Xenopus laevis oocytes injected with CHIP28 RNA exhibit high osmotic water permeability, Pf [Preston et al. (1992) Science …

Water channel proteins: from their discovery in 1985 in …

WebSep 2, 2024 · Appearance of Water Channels in Xenopus Oocytes Expressing Red Cell CHIP28 Protein. 3. The Aquaporins, Blueprints for Cellular Plumbing Systems. 4. Molecular structure of the water channel through aquaporin CHIP. The hourglass model. 5. Aquaporin water channels – from atomic structure to clinical medicine WebApr 1, 1992 · The CHIP28 protein is an abundant integral membrane protein in mammalian RBCs and renal proximal tubules and belongs to a family of membrane proteins with unknown functions. Oocytes from Xenopus laevis microinjected with in vitro-transcribed CHIP28 RNA exhibited increased osmotic water permeability; this was reversibly … the potty song peppa pig

Reconstitution of functional water channels in liposomes ... - PubMed

WebCHIP28 is found in basolateral and apical plasma membranes of kidney proximal tubules and thin descending limbs of Henle, whereas WCH-CD is apically located in collecting duct principal cells. So far, the putative water channel that may be responsible for the high constitutive permeability of principal cell basolateral membranes has not been ... WebJan 2, 1993 · The sites of water transport along the nephron are well characterized, but the molecular basis of renal water transport remains poorly understood. CHIP28 is a 28-kD … WebThese studies demonstrated: (i) CHIP28 water channel activity is retained despite substitution of individual cysteines with serine; (ii) cysteine 189 is the Hg(2+)-sensitive … siem online training

From Membrane Pores to Aquaporins: 50 Years Measuring …

The mercury-sensitive residue at cysteine 189 in the CHIP28 …

WebNov 15, 1991 · The 28-kD integral membrane protein CHIP28 is abundant in mammalian RBCs and renal proximal tubules (11). The na-tive CHIP28 protein is a noncovalent as … WebJan 2, 1993 · CHIP28 comprised 3.8% of isolated proximal tubule brush border protein. Except for the first few cells of the S1 segment, CHIP28 was immunolocalized throughout the convoluted and straight proximal tubules where it was observed in the microvilli of the apical brush border and in basolateral membranes. the potty song once upon a potty siemon network cable

"WebThe magnitude of CHIP28-mediated water flux (11.7 X 10-14 cm3/s per CHIP28) corresponds to the known Pf of intact RBCs. These results demonstrate that CHIP28 … " - Chip28 protein

Chip28 protein

Appearance of Water Channels in Xenopus Oocytes …

WebMay 9, 2008 · Abstract. This review focuses on studies of water movement across biological membranes performed over the last 50 years. Different scientific approaches had tried to elucidate such intriguing mechanism, from hypotheses emphasizing the role of the lipid bilayer to the cloning of aquaporins, the ubiquitous proteins described as specific water ... WebInformation on the Nobel Prize in Chemistry 2003. WATER CHANNELS. Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein by G.M. Preston, T.P. Carroll, W.B. Guggino, and P. …

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WebThe native CHIP28 protein is a noncovalent assembly of four subunits (12) and is physically similar to certain membrane channels (hence, CHIP28 = channel-forming integral protein of 28 kD). The cDNA encoding CHIP28 has been isolated (13), and the deduced amino acid sequence predicts an integral membrane protein with six bilayerspanning domains ... WebDec 15, 1991 · A cDNA for CHIP28 was isolated from human fetal liver cDNA template by a three-step polymerase chain reaction (PCR) cloning strategy, starting with degenerate …

WebCustomer Help and Information Program. channel-forming integral protein of 28 kDa. Child Health and Illness Profile, Adolescent Edition. Camp Hill Information Processing Center. … WebLIN28A. LIN28A (previously LIN28 ), originally found in Caenorhabditis elegans, encodes an RNA-binding protein [protein lin-28 homolog A (Lin-28A)] that has been characterized …

WebJun 17, 2014 · 第一章文献综述 AQ PI又称通道形成整合蛋I刍（channel forming integra protein，CHIP28），其分子中含有269个氨基酸残基，是红细胞膜的主要水通道蛋白，主要在系统的毛细血管与小血管的上皮细胞有广泛表达，冈此在消化系统13“51、呼吸系统、中枢神经系统【6】都有 ... WebApr 17, 1992 · The CHIP28 protein is an abundant integral membrane protein in mammalian RBCs and renal proximal tubules and belongs to a family of membrane …

WebInformation on the Nobel Prize in Chemistry 2003. WATER CHANNELS. Appearance of water channels in Xenopus oocytes expressing red cell …

WebOct 8, 2024 · CHIP28 is a 28-kD hydrophobic integral membrane protein that functions as a water channel in erythrocytes and renal tubule epithelial cell membranes. We … the potty storeWebJan 1, 2001 · Abstract. CHIP28 is a 28-kDa integral membrane protein with similarities to membrane channels and is found in erythrocytes and renal tubules. A cDNA for CHIP28 was isolated from human fetal liver cDNA template by a three-step polymerase chain reaction (PCR) cloning strategy, starting with degenerate oligonucleotide primers corresponding … siem on opensearch service 料金WebOct 30, 2006 · We have thus a world priority in the discovery of the first water channel in the RBC membrane, that was re-discovered by chance by the group of Agre (Baltimore, … siemon s814 impact toolWebIn 1992 Peter Agre conducted an elegant experiment in which he kept, in water, frog oocytes into which he had introduced a membrane protein called CHIP28. After some minutes … the potty trainerWebOct 30, 2006 · However, in addition to the 28 kDa component, this protein had a 35-60 kDa glycosylated component, the one detected by Benga's group. Only in 1992 the Agre's group suggested that "it is likely that CHIP28 is a functional unit of membrane water channels". In 1993 CHIP28 was renamed aquaporin 1. the potty stoolWebJun 1, 1993 · The coinjection of an antisense oligonucleotide for CHIP28 protein, at an assumed > 100-fold molar excess, with either cortex, medulla, or papilla mRNA reduced the expression of the water permeability by approximately 70, 100, and 30%, respectively. Exposure of the oocyte to cAMP for 1 h resulted in a further increase in Pf only in oocytes ... the potty training answer bookWebMost aquaporins have a protein kinase A phosphorylation motif in one of the cytoplasmic loops, and differential phosphorylation is suspected empart a regulatory function to the molecule. ... Appearance of water channels … the potty train