WebThis was confirmed on multivariable analysis, which revealed that extraprostatic extension was a significant independent predictor of biochemical recurrence (HR 1.53, p=0.018). The presence of pseudocapsular invasion had no effect (HR 0.81, p=0.33). WebExtraprostatic extension Abbreviated EPE. General. Extraprostatic extension (EPE) is difficult to assess in prostatectomy specimens. The prostate does NOT have a well defined capsule. Intraobserver agreement for EPE is fair-moderate and lower than for the surgical margin. EPE, typically, upstages tumours from T2x to T3a. Prostatectomy specimens

Computational Detection of Extraprostatic Extension of Prostate …

WebMar 10, 2009 · Proliferation of relatively uniform small glands lined by a single layer of cells Cells with prominent nucleoli, components of the nucleus that help build proteins Enlarged nuclei Lack of basal cells, which sit below the epithelium in normal tissue Cells that stain readily with dyes Evidence of perineural invasion (PNI). WebPresence of carcinoma at the level of fat is diagnostic of extraprostatic extension; Skeletal muscle may be seen in normal prostate and is not useful; Perineural invasion indicates 95% probability of extraprostatic extension It should be reported for needle biopsy specimens; Invasion of seminal vesicle – must rule out identical appearing ... reformed churches in us

Radical prostatectomy for carcinoma of the prostate

WebThe presence of extraprostatic extension (EPE) on multiparametric MRI (mpMRI) is an important factor in determining the management of prostate cancer. EPE is an … WebORIGINAL RESEARCH Evaluation of MRI for Diagnosis of Extraprostatic Extension in Prostate Cancer Satheesh Krishna, MD,1 Christopher S. Lim, BMBS ,1 Matthew D.F. McInnes, MD,1 Trevor A. Flood, MD,2 Wael M. Shabana, MD,1 Robert S. Lim, MBBS,1 and Nicola Schieda, MD1* Purpose: To assess the ability of magnetic resonance imaging … reformed commentaries